Abstract Human telomere length is tightly regulated and associated with diseases at either extreme, but how these bounds are established remains incompletely understood.Here, we developed a rapid cell-based telomere synthesis assay and found that nucleoside salvage bidirectionally constrains human telomere length.Metabolism of deoxyguanosine (dG) o
The high-level biosafety laboratory is not only the basic support for infectious disease prevention and control, but also interrelated with key areas such as environmental security and social security, which has attracted increasing attention.A good indoor environment is the premise to ensure the smooth progress of the experiment and biological ris
Numerous cases of acute renal failure in dogs and cats from 2004-2007 were associated with the ingestion of dog and cat pet food products and the suspected contaminant was identified as melamine and its derivatives such as cyanuric acid and melamine cyanurate.Melamine is a chemical used primarily for the manufacture of plastics, coatings, commercia
Diatoms are an important class of unicellular Solutions algae that produce bioactive polyunsaturated aldehydes (PUAs) that induce abortions or malformations in the offspring of invertebrates exposed to them during gestation.Here we compare the effects of the PUAs 2-trans,4-trans-decadienal (DD), 2-trans,4-trans-octadienal (OD) and 2-trans,4-trans-h
The molds used in the manufacture of many industrial products are mainly Little Board Wire manufactured by cutting with a machining center.Since the cutting time is very long in these cutting processes, it is important to judge the tool life and know the appropriate timing for tool change.The authors of this study have been investigating in-process